Drug Information

Drug General Information
Drug ID
D03OLU
Former ID
DIB020814
Drug Name
RN1734
Synonyms
RN 1734; RN-1734
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467633]
Structure
Download
2D MOL
Formula
C14H22Cl2N2O2S
InChI
InChI=1S/C14H22Cl2N2O2S/c1-10(2)17-7-8-18(11(3)4)21(19,20)14-6-5-12(15)9-13(14)16/h5-6,9-11,17H,7-8H2,1-4H3
InChIKey
IHYZMEAZAIFMTN-UHFFFAOYSA-N
PubChem Compound ID
3601086
PubChem Substance ID
4894060, 9760968, 79663598, 89738374, 109657980, 112026062, 118767587, 125479939, 129983755, 135697961, 162248968, 163243860, 164131536, 164155450, 165825013, 172088882, 178101111, 187072862, 250230356, 252157504
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily V member 4 Target Info Blocker (channel blocker) [530364]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 467633(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4294).
Ref 530364Identification and characterization of novel TRPV4 modulators. Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4.

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