Drug Information

Drug General Information
Drug ID
D09DAP
Former ID
DIB018769
Drug Name
AG-09/1
Synonyms
AG-09/1 [benzimidazole derivative]; ST024252
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541152]
Structure
Download
2D MOL
Formula
C16H14N4O4S
InChI
InChI=1S/C16H14N4O4S/c1-24-12-6-7-13-14(8-12)19-16(18-13)25-9-15(21)17-10-2-4-11(5-3-10)20(22)23/h2-8H,9H2,1H3,(H,17,21)(H,18,19)
InChIKey
LYQDSNOFTIZWAX-UHFFFAOYSA-N
PubChem Compound ID
3901842
PubChem Substance ID
5717238, 6437343, 10003997, 24334573, 35100643, 47243189, 48463898, 48773695, 52428080, 57991841, 71844142, 88470687, 90535175, 96044599, 105377890, 106216558, 112464652, 123091776, 124525844, 162249015, 169270493, 178102458
Target and Pathway
Target(s) FMLP receptor Target Info Agonist [530510]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway Leptin Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Human Complement System
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 541152(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5833).
Ref 530510Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition. Mol Pharmacol. 2010 Feb;77(2):159-70.

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