Drug General Information
Drug ID	D0M8UY
Former ID	DNC009264
Drug Name	6-hydroxybenzo[d][1,3]oxathiol-2-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529555]
Structure		Download 2D MOL 3D MOL
Formula	C7H4O3S
Canonical SMILES	C1=CC2=C(C=C1O)OC(=O)S2
InChI	1S/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H
InChIKey	SLYPOVJCSQHITR-UHFFFAOYSA-N
PubChem Compound ID	72139
Target and Pathway
Target(s)	Carbonic anhydrase II	Target Info	Inhibitor	[529555]
KEGG Pathway	Nitrogen metabolism
	Proximal tubule bicarbonate reclamation
	Collecting duct acid secretion
	Gastric acid secretion
	Pancreatic secretion
	Bile secretion
NetPath Pathway	IL4 Signaling Pathway
	EGFR1 Signaling Pathway
Reactome	Erythrocytes take up carbon dioxide and release oxygen
	Erythrocytes take up oxygen and release carbon dioxide
	Reversible hydration of carbon dioxide
WikiPathways	Reversible Hydration of Carbon Dioxide
	Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
	Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 529555	Bioorg Med Chem Lett. 2008 Jul 15;18(14):3938-41. Epub 2008 Jun 12.Carbonic anhydrase inhibitors: thioxolone versus sulfonamides for obtaining isozyme-selective inhibitors?.
Ref 529555	Bioorg Med Chem Lett. 2008 Jul 15;18(14):3938-41. Epub 2008 Jun 12.Carbonic anhydrase inhibitors: thioxolone versus sulfonamides for obtaining isozyme-selective inhibitors?.

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