Drug Information

Drug General Information
Drug ID
D0V9LR
Former ID
DIB019501
Drug Name
compound 42
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531844], [541113]
Structure
Download
2D MOL
Formula
C22H24Cl2N4O2
InChI
InChI=1S/C22H24Cl2N4O2/c1-14-17(22(29)25-9-10-30-16-5-3-2-4-6-16)12-26-21-18(13-27-28(14)21)15-7-8-19(23)20(24)11-15/h2-6,12-13,15,19-20H,7-11H2,1H3,(H,25,29)
InChIKey
BHDJYYFELGTSTL-UHFFFAOYSA-N
PubChem Compound ID
73755156
PubChem Substance ID
178102419
Target and Pathway
Target(s) Nicotinic acid receptor 1 Target Info Modulator (allosteric modulator) [531844]
KEGG Pathway cAMP signaling pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
References
Ref 531844Novel 3,6,7-substituted pyrazolopyrimidines as positive allosteric modulators for the hydroxycarboxylic acid receptor 2 (GPR109A). J Med Chem. 2012 Apr 12;55(7):3563-7.
Ref 541113(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5794).
Ref 531844Novel 3,6,7-substituted pyrazolopyrimidines as positive allosteric modulators for the hydroxycarboxylic acid receptor 2 (GPR109A). J Med Chem. 2012 Apr 12;55(7):3563-7.

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