Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0P5UW
|
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| Former ID |
DNC007165
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| Drug Name |
ECOPLADIB
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [529940] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C39H33Cl3N2O5S
|
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| Canonical SMILES |
C1=CC=C(C=C1)C(C2=CC=CC=C2)N3C4=C(C=C(C=C4)Cl)C(=C3CCNS<br />(=O)(=O)CC5=CC(=C(C=C5)Cl)Cl)CCOC6=CC=C(C=C6)C(=O)O
|
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| InChI |
1S/C39H33Cl3N2O5S/c40-30-14-18-36-33(24-30)32(20-22-49-31-15-12-29(13-16-31)39(45)46)37(19-21-43-50(47,48)25-26-11-17-34(41)35(42)23-26)44(36)38(27-7-3-1-4-8-27)28-9-5-2-6-10-28/h1-18,23-24,38,43H,19-22,25H2,(H,45,46)
|
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| InChIKey |
FMMCHWHNSUBYAV-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cytosolic phospholipase A2 | Target Info | Inhibitor | [529940] | |
| BioCyc Pathway | Phospholipases | ||||
| KEGG Pathway | Glycerophospholipid metabolism | ||||
| Ether lipid metabolism | |||||
| Arachidonic acid metabolism | |||||
| Linoleic acid metabolism | |||||
| alpha-Linolenic acid metabolism | |||||
| Metabolic pathways | |||||
| MAPK signaling pathway | |||||
| Ras signaling pathway | |||||
| Vascular smooth muscle contraction | |||||
| VEGF signaling pathway | |||||
| Platelet activation | |||||
| Fc epsilon RI signaling pathway | |||||
| Fc gamma R-mediated phagocytosis | |||||
| Glutamatergic synapse | |||||
| Serotonergic synapse | |||||
| Long-term depression | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| GnRH signaling pathway | |||||
| Ovarian steroidogenesis | |||||
| Oxytocin signaling pathway | |||||
| Choline metabolism in cancer | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
| Endothelins | |||||
| PDGFR-beta signaling pathway | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| PathWhiz Pathway | Fc Epsilon Receptor I Signaling in Mast Cells | ||||
| References | |||||
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