Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0AR3J
|
||||
| Former ID |
DAP000465
|
||||
| Drug Name |
Ouabain
|
||||
| Synonyms |
Acocantherin; Acocantherine; Astrobain; Gratibain; Kombetin; OBN; Ouabaine; Oubain; Purostrophan; Quabain; Rectobaina; Solufantina; Strodival; Strophalen; Strophoperm; Strophosan; Uabaina; Uabanin; Acolongifloroside K; Gratus strophanthin; Ouabain anhydrous; Ouabain octahydrate; Strophanthin G; O 3125; G-Strophanthin; G-Strophicor; Ouabagenin L-Rhamnoside; Ouabagenin L-rhamnoside; Ouabain (anhydrous); Ouabain, Octahydrate; Strophanthin-G; G-Strophanthin (JAN); Ouabagenin-L-rhamnosid; Ouabagenin-L-rhamnosid [German]; 3-((6-deoxyhexopyranosyl)oxy)-1,5,11,14,19-pentahydroxycard-20(22)-enolide; 3-[(6-Deoxyhexopyranosyl)oxy]-1,5,11,14,19-pentahydroxycard-20(22)-enolide
|
||||
| Drug Type |
Small molecular drug
|
||||
| Therapeutic Class |
Cardiotonic Agents
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C29H44O12
|
||||
| InChI |
InChI=1S/C29H44O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-/m0/s1
|
||||
| InChIKey |
LPMXVESGRSUGHW-HBYQJFLCSA-N
|
||||
| CAS Number |
CAS 630-60-4
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID |
4621, 598376, 7847180, 7889527, 7980210, 8011283, 10298350, 11466499, 11467619, 11486277, 11533037, 14838096, 15981102, 17405501, 24278610, 26746568, 29204593, 36883713, 46392206, 46505479, 47291380, 47736758, 48035407, 48035408, 48185244, 48334784, 49698509, 49834233, 53778049, 53787305, 57287889, 57403052, 75081902, 85182289, 85231346, 85788049, 87351514, 87575707, 90340653, 92092794, 92304198, 92308875, 95614231, 99431516, 103511767, 104038270, 104128310, 104620666, 121361712, 121404260
|
||||
| ChEBI ID |
ChEBI:7805
|
||||
| SuperDrug ATC ID |
C01AC01
|
||||
| SuperDrug CAS ID |
cas=000630604
|
||||
| Target and Pathway | |||||
| Target(s) | Sodium/potassium-transporting ATPase alpha-1 chain | Target Info | Binder | [536316] | |
| KEGG Pathway | cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | |||||
| Cardiac muscle contraction | |||||
| Adrenergic signaling in cardiomyocytes | |||||
| Insulin secretion | |||||
| Thyroid hormone synthesis | |||||
| Thyroid hormone signaling pathway | |||||
| Aldosterone-regulated sodium reabsorption | |||||
| Endocrine and other factor-regulated calcium reabsorption | |||||
| Proximal tubule bicarbonate reclamation | |||||
| Salivary secretion | |||||
| Gastric acid secretion | |||||
| Pancreatic secretion | |||||
| Carbohydrate digestion and absorption | |||||
| Protein digestion and absorption | |||||
| Bile secretion | |||||
| Mineral absorption | |||||
| Reactome | Ion transport by P-type ATPases | ||||
| WikiPathways | Iron uptake and transport | ||||
| References | |||||
| Ref 468058 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4826). | ||||
| Ref 550772 | Drug information of Ouabain, 2008. eduDrugs. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.