Drug Information

Drug General Information
Drug ID
D06DRY
Former ID
DIB019869
Drug Name
FP0429
Synonyms
FP 0429; FP-0429
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538885]
Structure
Download
2D MOL
Formula
C10H12N2O7
InChI
InChI=1S/C10H12N2O7/c11-10(9(18)19)3-5(8(16)17)12(4-10)6(13)1-2-7(14)15/h1-2,5H,3-4,11H2,(H,14,15)(H,16,17)(H,18,19)/b2-1+/t5-,10-/m0/s1
InChIKey
ZALHFQNLXQORTH-FGLATXDZSA-N
PubChem Compound ID
11565290
PubChem Substance ID
16667539, 23684129, 42707170, 75837640, 103498604, 104074218, 135650282, 141428181, 230569154
Target and Pathway
Target(s) Metabotropic glutamate receptor 4 Target Info Agonist [528577]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
Taste transduction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Metabotropic glutamate receptor group III pathway
Reactome G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
GPCR ligand binding
GPCR downstream signaling
References
Ref 538885(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1409).
Ref 528577Amino-pyrrolidine tricarboxylic acids give new insight into group III metabotropic glutamate receptor activation mechanism. Mol Pharmacol. 2007 Mar;71(3):704-12. Epub 2006 Dec 13.

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