Drug Information

Drug General Information
Drug ID
D0P7NP
Former ID
DNC011265
Drug Name
CP-305202
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531120]
Structure
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2D MOL

3D MOL
Formula
C30H44N2O5
Canonical SMILES
CC(C)CC(C(C(CC1CCCCC1)NC(=O)C2=C(C=CC=C2OCCCC3=CN=CC=C3<br />)OC)O)O
InChI
1S/C30H44N2O5/c1-21(2)18-25(33)29(34)24(19-22-10-5-4-6-11-22)32-30(35)28-26(36-3)14-7-15-27(28)37-17-9-13-23-12-8-16-31-20-23/h7-8,12,14-16,20-22,24-25,29,33-34H,4-6,9-11,13,17-19H2,1-3H3,(H,32,35)/t24-,25-,29+/m0/s1
InChIKey
PJZBKGNAKHKHSH-IALVYGIMSA-N
PubChem Compound ID
52948369
Target and Pathway
Target(s) Renin, renal Target Info Inhibitor [531120]
KEGG Pathway Renin-angiotensin system
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 531120J Med Chem. 2010 Nov 11;53(21):7490-520.Direct renin inhibitors as a new therapy for hypertension.
Ref 531120J Med Chem. 2010 Nov 11;53(21):7490-520.Direct renin inhibitors as a new therapy for hypertension.

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