Drug Information

Drug General Information
Drug ID
D0A7NH
Former ID
DNC010101
Drug Name
4-(Cyclohexylamino)-1-naphthol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530623]
Structure
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2D MOL

3D MOL
Formula
C16H19NO
Canonical SMILES
C1CCC(CC1)NC2=CC=C(C3=CC=CC=C32)O
InChI
1S/C16H19NO/c18-16-11-10-15(13-8-4-5-9-14(13)16)17-12-6-2-1-3-7-12/h4-5,8-12,17-18H,1-3,6-7H2
InChIKey
JNIUFYOCOKGFDL-UHFFFAOYSA-N
PubChem Compound ID
45487176
Target and Pathway
Target(s) Indoleamine 2,3-dioxygenase Target Info Inhibitor [530623]
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation
L-kynurenine degradation
Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
NAD de novo biosynthesis
KEGG Pathway Tryptophan metabolism
Metabolic pathways
African trypanosomiasis
NetPath Pathway TSLP Signaling Pathway
IL5 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Tryptophan Metabolism
Reactome Tryptophan catabolism
WikiPathways Tryptophan metabolism
Metabolism of amino acids and derivatives
References
Ref 530623J Med Chem. 2010 Feb 11;53(3):1172-89.Rational design of indoleamine 2,3-dioxygenase inhibitors.
Ref 530623J Med Chem. 2010 Feb 11;53(3):1172-89.Rational design of indoleamine 2,3-dioxygenase inhibitors.

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