Drug Information
Drug General Information | |||||
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Drug ID |
D0A4IJ
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Former ID |
DAP000704
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Drug Name |
Abacavir
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Synonyms |
Trizivir; Ziagen; Abacavir [INN]; Abacavir (INN); Ziagen (TN); Ziagen (TM)(*Succinate salt*); [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol; {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol; (+/-)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (+/-)-Abacavir; (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; ABC
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Drug Type |
Small molecular drug
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Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Approved | [550653] | ||
Therapeutic Class |
Anti-HIV Agents
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Company |
GlaxoSmithKline
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Structure |
Download2D MOL |
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Formula |
C14H18N6O
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Canonical SMILES |
C1CC1NC2=NC(=NC3=C2N=CN3C4CC(C=C4)CO)N
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InChI |
1S/C14H18N6O/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21/h1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19)/t8-,10+/m1/s1
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InChIKey |
MCGSCOLBFJQGHM-SCZZXKLOSA-N
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CAS Number |
CAS 136470-78-5
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PubChem Compound ID | |||||
PubChem Substance ID |
9826, 603460, 612310, 7978623, 10298786, 14775540, 14799909, 26757979, 26757980, 36885172, 46505718, 51091399, 57403623, 70504220, 76364492, 81092778, 85612588, 92729708, 103463308, 104052305, 104625144, 126654052, 128575040, 131298145, 135025044, 136345668, 137006087, 142178555, 160845918, 160964383, 162011475, 162176802, 163621096, 163686421, 163883088, 164814948, 165235811, 175267614, 175442679, 179149865, 184545024, 186014779, 196109919, 223516662, 223703089, 223704757, 223900945, 226424139, 241033176, 241383802
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ChEBI ID |
ChEBI:2360
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SuperDrug ATC ID |
J05AF06
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SuperDrug CAS ID |
cas=136470785
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Drug Resistance Mutation (DRM) | |||||
DRM | DRM Info | ||||
Target and Pathway | |||||
Target(s) | HIV reverse transcriptase | Target Info | Inhibitor | [537321] | |
References |
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