Drug Information
Drug General Information | |||||
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Drug ID |
D04OVJ
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Former ID |
DNC003516
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Drug Name |
Ro-154513
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [467635] | ||
Formula |
C15H14N6O3
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InChI |
InChI=1S/C15H14N6O3/c1-3-24-15(23)13-12-7-20(2)14(22)10-6-9(18-19-16)4-5-11(10)21(12)8-17-13/h4-6,8H,3,7H2,1-2H3
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InChIKey |
CFSOJZTUTOQNIA-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
7380059, 8153126, 12013972, 14924107, 24899343, 26753182, 29224150, 48110695, 48334739, 49978810, 53790684, 56464704, 56464705, 57322599, 77036011, 91722218, 103164360, 104308223, 125541711, 127618661, 134340721, 134961914, 135062199, 135697913, 162023141, 162228348, 163201388, 177748542, 178101113, 178101180, 184581957, 198958950, 239972838, 241375734, 252156245
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Target and Pathway | |||||
Target(s) | Gamma-aminobutyric acid receptor subunit beta-2 | Target Info | Inhibitor | [534008] | |
Gamma-aminobutyric-acid receptor alpha-5 subunit | Target Info | Inhibitor | [534122] | ||
Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Inhibitor | [534008] | ||
Gamma-aminobutyric acid receptor subunit gamma-2 | Target Info | Inhibitor | [533912] | ||
Gamma-aminobutyric-acid receptor alpha-2 subunit | Target Info | Inhibitor | [534122] | ||
Gamma-aminobutyric acid receptor | Target Info | Inhibitor | [534122] | ||
Gamma-aminobutyric-acid receptor alpha-3 subunit | Target Info | Inhibitor | [534122] | ||
WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
Iron uptake and transportWP706:SIDS Susceptibility Pathways | |||||
Iron uptake and transport | |||||
References | |||||
Ref 533912 | J Med Chem. 1994 Mar 18;37(6):758-68.Antagonist, partial agonist, and full agonist imidazo[1,5-a]quinoxaline amides and carbamates acting through the GABAA/benzodiazepine receptor. | ||||
Ref 534008 | J Med Chem. 1993 Apr 16;36(8):1001-6.Synthesis and evaluation of imidazo[1,5-a][1,4]benzodiazepine esters with high affinities and selectivities at "diazepam-insensitive" benzodiazepine receptors. | ||||
Ref 534122 | J Med Chem. 1996 Apr 26;39(9):1928-34.Synthesis and pharmacological properties of novel 8-substituted imidazobenzodiazepines: high-affinity, selective probes for alpha 5-containing GABAA receptors. |
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