Drug General Information
Drug ID	D08AGA
Former ID	DNC011822
Drug Name	3-((S)-Azetidin-2-yloxy)-5-iodo-pyridine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527014]
Structure		Download 2D MOL 3D MOL
Formula	C8H9IN2O
Canonical SMILES	C1CNC1OC2=CC(=CN=C2)I
InChI	1S/C8H9IN2O/c9-6-3-7(5-10-4-6)12-8-1-2-11-8/h3-5,8,11H,1-2H2/t8-/m0/s1
InChIKey	KSOZTGQWGPTPSV-QMMMGPOBSA-N
PubChem Compound ID	44297909
Target and Pathway
Target(s)	Neuronal acetylcholinereceptor subunit alpha-2	Target Info	Inhibitor	[527014]
KEGG Pathway	Neuroactive ligand-receptor interaction
PANTHER Pathway	Nicotinic acetylcholine receptor signaling pathway
Reactome	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
	Highly calcium permeable nicotinic acetylcholine receptors
WikiPathways	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 527014	Bioorg Med Chem Lett. 2004 Apr 19;14(8):1845-8.Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.
Ref 527014	Bioorg Med Chem Lett. 2004 Apr 19;14(8):1845-8.Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.

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