Drug Information

Drug General Information
Drug ID
D00OMW
Former ID
DIB019939
Drug Name
group E 1682-2106
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527699], [541146]
Structure
Download
2D MOL
Formula
C17H16N2O4S2
InChI
InChI=1S/C17H16N2O4S2/c1-8(2)12(16(22)23)19-15(21)13(25-17(19)24)11-9-6-4-5-7-10(9)18(3)14(11)20/h4-8,12H,1-3H3,(H,22,23)/b13-11-
InChIKey
ICRQMQBVDGOOFY-QBFSEMIESA-N
PubChem Compound ID
5322194
PubChem Substance ID
7995979, 11058376, 39295227, 80258258, 87995986, 106747776, 114177742, 118450650, 131277482, 143666488, 163367388, 178102452, 181849647, 218870697
Target and Pathway
Target(s) FMLP receptor Target Info Antagonist [527699]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway Leptin Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Human Complement System
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 527699Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists. Mol Pharmacol. 2005 Nov;68(5):1301-10. Epub 2005 Aug 23.
Ref 541146(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5827).
Ref 527699Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists. Mol Pharmacol. 2005 Nov;68(5):1301-10. Epub 2005 Aug 23.

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