Drug Information
Drug General Information | |||||
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Drug ID |
D06RNM
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Former ID |
DIB019035
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Drug Name |
burimamide
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [538741] | ||
Structure |
Download2D MOL |
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Formula |
C13H18N4S
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InChI |
InChI=1S/C13H18N4S/c1-14-13(18)15-8-3-2-5-10-6-4-7-12-11(10)9-16-17-12/h4,6-7,9H,2-3,5,8H2,1H3,(H,16,17)(H2,14,15,18)
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InChIKey |
TXQIYKPZFOKCHA-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Histamine H4 receptor | Target Info | Antagonist | [526144] | |
Histamine H3 receptor | Target Info | Antagonist | [535111] | ||
Histamine H2 receptor | Target Info | Agonist | [534673] | ||
References | |||||
Ref 526144 | Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation. J Pharmacol Exp Ther. 2001 Oct;299(1):121-30. | ||||
Ref 534673 | Constitutive activity and structural instability of the wild-type human H2 receptor. J Neurochem. 1998 Aug;71(2):799-807. | ||||
Ref 535111 | Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow. Mol Pharmacol. 2001 Mar;59(3):420-6. |
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