Drug Information

Drug General Information
Drug ID
D0Q6NN
Former ID
DIB018040
Drug Name
TAK-070
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Clinical trial [531110]
Structure
Download
2D MOL
Formula
C27H31NO
InChI
InChI=1S/C27H31NO/c1-28(2)17-16-21-8-13-26-19-27(15-14-25(26)18-21)29-20-22-9-11-24(12-10-22)23-6-4-3-5-7-23/h3-7,9-12,14-15,19,21H,8,13,16-18,20H2,1-2H3/t21-/m0/s1
InChIKey
SETMAZMOXYOEJA-NRFANRHFSA-N
PubChem Compound ID
10112962
PubChem Substance ID
15125915, 22518653, 39752035, 76698684, 143244406, 178103522, 226693808, 246628245, 249817361, 249820026
Target and Pathway
Target(s) Beta-secretase Target Info Inhibitor [531110]
References
Ref 531110A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer's disease. J Neurosci. 2010 Aug 18;30(33):11157-66.
Ref 531110A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer's disease. J Neurosci. 2010 Aug 18;30(33):11157-66.

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