Drug Information

Drug General Information
Drug ID
D01ZHW
Former ID
DIB020490
Drug Name
N-arachidonoylglycine
Synonyms
NAGly
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540488]
Structure
Download
2D MOL
Formula
C22H35NO3
InChI
InChI=1S/C22H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(24)23-20-22(25)26/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-20H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-,13-12-,16-15-
InChIKey
YLEARPUNMCCKMP-DOFZRALJSA-N
PubChem Compound ID
5283389
PubChem Substance ID
7850526, 11038952, 11110721, 14779114, 17404637, 26753513, 26753514, 26753515, 26753516, 39316800, 47588723, 47959441, 48034820, 50105803, 50105804, 50105805, 53777180, 57358918, 77161808, 85230900, 85787441, 90341148, 91148255, 91702858, 92303437, 92309860, 92741683, 99300774, 99302292, 99368434, 103410804, 103952742, 104046470, 104171102, 113859936, 124749424, 124879125, 124879126, 124879127, 124879128, 124879129, 124879130, 126525358, 137125130, 137796092, 144203621, 163564028, 170466894, 174811335, 178100542
Target and Pathway
Target(s) LPA5 receptor Target Info Agonist [529486]
GPR18 Target Info Agonist [528313]
References
Ref 540488(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3635).
Ref 528313Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18. Biochem Biophys Res Commun. 2006 Sep 1;347(3):827-32. Epub 2006 Jul 10.
Ref 529486Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92. J Biol Chem. 2008 Jul 25;283(30):21054-64.

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