Drug General Information
Drug ID
D04FBZ
Former ID
DNC000986
Drug Name
Nalorphine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539003]
Structure
Download
2D MOL

3D MOL

Formula
C19H21NO3
InChI
InChI=1S/C19H21NO3/c1-2-8-20-9-7-19-12-4-6-15(22)18(19)23-17-14(21)5-3-11(16(17)19)10-13(12)20/h2-6,12-13,15,18,21-22H,1,7-10H2/t12-,13+,15-,18-,19-/m0/s1
InChIKey
UIQMVEYFGZJHCZ-SSTWWWIQSA-N
CAS Number
CAS 62-67-9
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
V03AB02
SuperDrug CAS ID
cas=000062679
Target and Pathway
Target(s) Kappa-type opioid receptor Target Info Agonist [534939]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Opioid prodynorphin pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539003(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1629).
Ref 534939Apparent efficacy of kappa-opioid receptor ligands on serum prolactin levels in rhesus monkeys. Eur J Pharmacol. 1999 Nov 3;383(3):305-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.