Drug Information

Drug General Information
Drug ID
D0U1LB
Former ID
DNC000920
Drug Name
Meglitinide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535457], [535692]
Structure
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2D MOL

3D MOL
Formula
C17H16ClNO4
Canonical SMILES
COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)C(=O)O
InChI
1S/C17H16ClNO4/c1-23-15-7-6-13(18)10-14(15)16(20)19-9-8-11-2-4-12(5-3-11)17(21)22/h2-7,10H,8-9H2,1H3,(H,19,20)(H,21,22)
InChIKey
SWLAMJPTOQZTAE-UHFFFAOYSA-N
CAS Number
CAS 54870-28-9
PubChem Compound ID
41214
PubChem Substance ID
7979884, 8176982, 12015467, 14924472, 34706879, 49886456, 53619121, 57312524, 93041310, 103394414, 104336385, 117460715, 126416115, 129298599, 134224981, 134338778, 134340208, 135003046, 137231470, 142710612, 179150609, 198951658, 226423603, 241095530, 249757752, 251960696
Target and Pathway
Target(s) SUR2-type K(ATP) channel Target Info Blocker [535457], [535692]
References
Ref 535457Pharmacological modulation of K(ATP) channels. Biochem Soc Trans. 2002 Apr;30(2):333-9.
Ref 535692Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides. J Physiol. 2003 Feb 15;547(Pt 1):159-68. Epub 2003 Jan 10.
Ref 535457Pharmacological modulation of K(ATP) channels. Biochem Soc Trans. 2002 Apr;30(2):333-9.
Ref 535692Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides. J Physiol. 2003 Feb 15;547(Pt 1):159-68. Epub 2003 Jan 10.

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