Drug Information
Drug General Information | |||||
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Drug ID |
D0J1PJ
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Former ID |
DNC001481
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Drug Name |
U50,488H
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539022] | ||
Structure |
Download2D MOL |
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Formula |
C19H26Cl2N2O
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InChI |
InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1
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InChIKey |
VQLPLYSROCPWFF-QZTJIDSGSA-N
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CAS Number |
CAS 83913-06-8
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Kappa-type opioid receptor | Target Info | Agonist | [534904], [535113] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
References | |||||
Ref 534904 | Effects of kappa- and mu-opioid receptor agonists on Ca2+ channels in neuroblastoma cells: involvement of the orphan opioid receptor. Eur J Pharmacol. 1999 Aug 27;379(2-3):191-8. | ||||
Ref 535113 | The selective kappa-opioid receptor agonist U50,488H attenuates voluntary ethanol intake in the rat. Behav Brain Res. 2001 May;120(2):137-46. |
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