Drug General Information
Drug ID
D03YVB
Former ID
DIB020005
Drug Name
HG-9-91-01
Synonyms
HY-15776
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532067]
Structure
Download
2D MOL
Formula
C32H37N7O3
InChI
InChI=1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-14,19-21H,15-18H2,1-5H3,(H,36,40)(H,33,34,35)
InChIKey
UYUHRKLITDJEHB-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Salt inducible kinase 2 Target Info Inhibitor [532067]
SIK family kinase 3 Target Info Inhibitor [532067]
salt-inducible kinase 1 Target Info Inhibitor [532067]
Pathway Interaction Database LKB1 signaling events
References
Ref 532067Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16986-91.
Ref 532067Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16986-91.

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