Drug General Information
Drug ID
D0PG8M
Former ID
DNC014326
Drug Name
4',4-Dihydroxychalcone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530713]
Structure
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2D MOL

3D MOL

Formula
C15H12O3
Canonical SMILES
C1=CC(=CC=C1C=CC(=O)C2=CC=C(C=C2)O)O
InChI
1S/C15H12O3/c16-13-6-1-11(2-7-13)3-10-15(18)12-4-8-14(17)9-5-12/h1-10,16-17H/b10-3+
InChIKey
FZQLEXXZAVVCCA-XCVCLJGOSA-N
PubChem Compound ID
Target and Pathway
Target(s) Tyrosine oxidase Target Info Inhibitor [530713]
BioCyc Pathway (S)-reticuline biosynthesis
Eumelanin biosynthesis
L-dopachrome biosynthesis
KEGG Pathway Tyrosine metabolism
Riboflavin metabolism
Metabolic pathways
Melanogenesis
PathWhiz Pathway Riboflavin Metabolism
Tyrosine Metabolism
WikiPathways Dopamine metabolism
References
Ref 530713Eur J Med Chem. 2010 May;45(5):2010-7. Epub 2010 Jan 28.Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone.
Ref 530713Eur J Med Chem. 2010 May;45(5):2010-7. Epub 2010 Jan 28.Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone.

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