Drug Information

Drug General Information
Drug ID
D03PLV
Former ID
DNC003221
Drug Name
1-Deaza-Adenosine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C11H14N4O4
Canonical SMILES
C1=CN=C2C(=C1N)N=CN2C3C(C(C(O3)CO)O)O
InChI
1S/C11H14N4O4/c12-5-1-2-13-10-7(5)14-4-15(10)11-9(18)8(17)6(3-16)19-11/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13)/t6-,8-,9-,11-/m1/s1
InChIKey
NVUDDRWKCUAERS-PNHWDRBUSA-N
PubChem Compound ID
159738
PubChem Substance ID
616906, 7885080, 10253735, 15247408, 26702390, 26756663, 46234934, 46391416, 47662497, 47885593, 57348804, 75018344, 103124968, 103124969, 103336466, 103955929, 113443121, 117523099, 134223350, 135115376, 241377021, 249618211, 252158105
Target and Pathway
Target(s) Adenosine deaminase Target Info Inhibitor [551393]
BioCyc Pathway Purine nucleotides degradation
Purine deoxyribonucleosides degradation
Purine ribonucleosides degradation to ribose-1-phosphate
Adenosine nucleotides degradation
Superpathway of purine nucleotide salvage
Adenine and adenosine salvage III
KEGG Pathway Purine metabolism
Metabolic pathways
Primary immunodeficiency
NetPath Pathway TCR Signaling Pathway
IL2 Signaling Pathway
PANTHER Pathway Adenine and hypoxanthine salvage pathway
Pathway Interaction Database p73 transcription factor network
C-MYB transcription factor network
Validated transcriptional targets of deltaNp63 isoforms
Validated transcriptional targets of TAp63 isoforms
PathWhiz Pathway Purine Metabolism
Reactome Purine salvage
WikiPathways Metabolism of nucleotides
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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