Drug Information

Drug General Information
Drug ID
D07HHD
Former ID
DIB020802
Drug Name
resolvin D2
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540820]
Structure
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2D MOL

3D MOL
Formula
C22H32O5
InChI
InChI=1S/C22H32O5/c1-2-3-9-16-20(24)21(25)17-12-7-5-4-6-10-14-19(23)15-11-8-13-18-22(26)27/h3-12,14,17,19-21,23-25H,2,13,15-16,18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,11-8-,14-10+,17-12+/t19-,20-,21?/m0/s1
InChIKey
IKFAUGXNBOBQDM-GIINMYNKSA-N
PubChem Compound ID
16061136
PubChem Substance ID
40649318, 126524493, 178102070, 179656489, 241163991
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Inhibitor (gating inhibitor) [531736]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 540820(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5417).
Ref 531736Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: distinct roles of resolvin D1, D2, and E1.J Neurosci. 2011 Dec 14;31(50):18433-8.

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