Drug Information

Drug General Information
Drug ID
D0Y1YR
Former ID
DIB019904
Drug Name
gingerol
Synonyms
[6]-Gingerol; 6-Gingerol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539557]
Structure
Download
2D MOL
Formula
C17H26O4
InChI
InChI=1S/C17H26O4/c1-3-4-5-6-14(18)12-15(19)9-7-13-8-10-16(20)17(11-13)21-2/h8,10-11,14,18,20H,3-7,9,12H2,1-2H3/t14-/m0/s1
InChIKey
NLDDIKRKFXEWBK-AWEZNQCLSA-N
PubChem Compound ID
442793
PubChem Substance ID
12645, 10299114, 11119953, 11120441, 11120929, 11121412, 11121892, 11147036, 11362481, 11365043, 11367605, 11370233, 11370234, 11373206, 11375767, 16813919, 26756480, 26756481, 36886224, 47515058, 47810480, 50111373, 50486041, 53790007, 56313390, 68530616, 85788022, 92309763, 99029918, 99300677, 99302195, 99452972, 103562733, 104151788, 104628376, 119501485, 126648014, 128718111, 131306502, 131485319, 135003383, 135049126, 135650304, 137054948, 142933381, 152027634, 162182991, 162221879, 163117666, 163614564
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Activator [527012]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 539557(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2428).
Ref 527012Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron. 2004 Mar 25;41(6):849-57.

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