Drug Information

Drug General Information
Drug ID
D08CNN
Former ID
DNC013431
Drug Name
1-(3-(phenylthio)propyl)-4-m-tolylpiperazine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528625]
Structure
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2D MOL

3D MOL
Formula
C20H26N2S
Canonical SMILES
CC1=CC(=CC=C1)N2CCN(CC2)CCCSC3=CC=CC=C3
InChI
1S/C20H26N2S/c1-18-7-5-8-19(17-18)22-14-12-21(13-15-22)11-6-16-23-20-9-3-2-4-10-20/h2-5,7-10,17H,6,11-16H2,1H3
InChIKey
ZHUHEUSMACZXIP-UHFFFAOYSA-N
PubChem Compound ID
10245844
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Inhibitor [528625]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 528625Bioorg Med Chem Lett. 2007 Mar 15;17(6):1708-12. Epub 2006 Dec 23.Synthesis and QSAR studies on hypotensive 1-[3-(4-substituted phenylthio) propyl]-4-(substituted phenyl) piperazines.
Ref 528625Bioorg Med Chem Lett. 2007 Mar 15;17(6):1708-12. Epub 2006 Dec 23.Synthesis and QSAR studies on hypotensive 1-[3-(4-substituted phenylthio) propyl]-4-(substituted phenyl) piperazines.

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