TTD | Drug: D0NY1J

Drug General Information
Drug ID	D0NY1J
Former ID	DIB021044
Drug Name	TG7-171
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[543191]
Structure		Download 2D MOL 3D MOL
Formula	C24H31N3O
InChI	InChI=1S/C24H31N3O/c1-4-26(5-2)22-13-11-20(12-14-22)18-24(28)25-15-8-16-27-19(3)17-21-9-6-7-10-23(21)27/h6-7,9-14,17H,4-5,8,15-16,18H2,1-3H3,(H,25,28)
InChIKey	NBHMEDLJHJCMEZ-UHFFFAOYSA-N
PubChem Compound ID	91827368
Target and Pathway
Target(s)	Prostaglandin E2receptor, EP2 subtype	Target Info	Antagonist	[532849]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Inflammatory mediator regulation of TRP channels
	Renin secretion
	Pathways in cancer
Reactome	Prostanoid ligand receptors
Reactome	G alpha (s) signalling events
WikiPathways	Prostaglandin Synthesis and Regulation
	GPCRs, Class A Rhodopsin-like
	Ovarian Infertility Genes
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543191	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8546).
Ref 532849	Development of second generation EP2 antagonists with high selectivity. Eur J Med Chem. 2014 Jul 23;82:521-35.

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Drug Information