Drug Information

Drug General Information
Drug ID
D0V8DH
Former ID
DIB020682
Drug Name
PF-4840154
Synonyms
PF4840154; PF 4840154
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541459]
Structure
Download
2D MOL
Formula
C26H38N6O2
InChI
InChI=1S/C26H38N6O2/c1-20(2)15-27-24-23(25(33)28-16-21-7-4-3-5-8-21)17-29-26(30-24)32-12-10-31(11-13-32)18-22-9-6-14-34-19-22/h3-5,7-8,17,20,22H,6,9-16,18-19H2,1-2H3,(H,28,33)(H,27,29,30)
InChIKey
PPANZCQXFYBGHN-UHFFFAOYSA-N
PubChem Compound ID
53380803
PubChem Substance ID
125303394, 134447543, 136357633, 178102928
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Activator [531547]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 541459(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6309).
Ref 531547Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4857-9.

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