Drug Information

Drug General Information
Drug ID
D03BIQ
Former ID
DNC006947
Drug Name
ADS-102891
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528581]
Structure
Download
2D MOL

3D MOL
Formula
C22H21F3N4O2
Canonical SMILES
CC1=NC(=NC2=C1C=C(C=C2)NC(=O)COC3=CC=C(C=C3)C(F)(F)F)N4<br />CCCC4
InChI
1S/C22H21F3N4O2/c1-14-18-12-16(6-9-19(18)28-21(26-14)29-10-2-3-11-29)27-20(30)13-31-17-7-4-15(5-8-17)22(23,24)25/h4-9,12H,2-3,10-11,13H2,1H3,(H,27,30)
InChIKey
UPUPELYLRJEQHO-UHFFFAOYSA-N
PubChem Compound ID
11189610
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Inhibitor [528581]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 528581Bioorg Med Chem Lett. 2007 Mar 1;17(5):1403-7. Epub 2006 Dec 2.Quinazoline and benzimidazole MCH-1R antagonists.
Ref 528581Bioorg Med Chem Lett. 2007 Mar 1;17(5):1403-7. Epub 2006 Dec 2.Quinazoline and benzimidazole MCH-1R antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.