Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00NVC
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| Former ID |
DNC004042
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| Drug Name |
Z-Ala-Leu-Nal-Agly-Ile-Val-OMe
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [526417] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C43H59N7O9
|
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| Canonical SMILES |
CCC(C)C(C(=O)NC(C(C)C)C(=O)OC)NC(=O)NNC(=O)C(CC1=CC=CC2<br />=CC=CC=C21)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)OCC3=CC=CC=C3
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| InChI |
1S/C43H59N7O9/c1-9-27(6)36(40(54)47-35(26(4)5)41(55)58-8)48-42(56)50-49-39(53)34(23-31-20-15-19-30-18-13-14-21-32(30)31)46-38(52)33(22-25(2)3)45-37(51)28(7)44-43(57)59-24-29-16-11-10-12-17-29/h10-21,25-28,33-36H,9,22-24H2,1-8H3,(H,44,57)(H,45,51)(H,46,52)(H,47,54)(H,49,53)(H2,48,50,56)
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| InChIKey |
KMJURIDKPLGXEZ-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cathepsin B | Target Info | Inhibitor | [526417] | |
| Cathepsin K | Target Info | Inhibitor | [526417] | ||
| Reactome | Collagen degradation | ||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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