Drug General Information
Drug ID	D01TSX
Former ID	DNC013349
Drug Name	(R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528778]
Structure		Download 2D MOL 3D MOL
Formula	C11H16INO2
Canonical SMILES	CC(CC1=CC(=C(C=C1OC)I)OC)N
InChI	1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1
InChIKey	BGMZUEKZENQUJY-SSDOTTSWSA-N
PubChem Compound ID	9840090
Target and Pathway
Target(s)	5-hydroxytryptamine 2A receptor	Target Info	Inhibitor	[528778]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and STAT3 Signaling
	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 528778	Bioorg Med Chem Lett. 2007 Jun 1;17(11):2998-3002. Epub 2007 Mar 25.Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity.
Ref 528778	Bioorg Med Chem Lett. 2007 Jun 1;17(11):2998-3002. Epub 2007 Mar 25.Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity.

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