Drug Information

Drug General Information
Drug ID
D06QLG
Former ID
DNC014120
Drug Name
Tyr-D-Ala-Gly-NMePhe
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530269]
Structure
Download
2D MOL

3D MOL
Formula
C21H26N4O4
Canonical SMILES
CC(C(=O)NCC(=O)N(C)C1=CC=CC=C1)NC(=O)C(CC2=CC=C(C=C2)O)<br />N
InChI
1S/C21H26N4O4/c1-14(24-21(29)18(22)12-15-8-10-17(26)11-9-15)20(28)23-13-19(27)25(2)16-6-4-3-5-7-16/h3-11,14,18,26H,12-13,22H2,1-2H3,(H,23,28)(H,24,29)/t14-,18+/m1/s1
InChIKey
OPRBFENCQHCQFV-KDOFPFPSSA-N
PubChem Compound ID
45483974
Target and Pathway
Target(s) Mu-type opioid receptor Target Info Inhibitor [530269]
KEGG Pathway Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addiction
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Pathway Interaction Database IL4-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways TCR Signaling Pathway
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
Opioid Signalling
GPCR ligand binding
GPCR downstream signaling
References
Ref 530269J Med Chem. 2009 Dec 10;52(23):7372-5.Discovery of dermorphin-based affinity labels with subnanomolar affinity for mu opioid receptors.
Ref 530269J Med Chem. 2009 Dec 10;52(23):7372-5.Discovery of dermorphin-based affinity labels with subnanomolar affinity for mu opioid receptors.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.