Drug General Information
Drug ID	D00FPG
Former ID	DNC006464
Drug Name	1-methyl-1H-indole-3-carboxamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528040]
Structure		Download 2D MOL 3D MOL
Formula	C10H10N2O
Canonical SMILES	CN1C=C(C2=CC=CC=C21)C(=O)N
InChI	1S/C10H10N2O/c1-12-6-8(10(11)13)7-4-2-3-5-9(7)12/h2-6H,1H3,(H2,11,13)
InChIKey	UHQHFXKJFJHBAE-UHFFFAOYSA-N
PubChem Compound ID	823187
Target and Pathway
Target(s)	Inosine-5'-monophosphate dehydrogenase 2	Target Info	Inhibitor	[528040]
BioCyc Pathway	Purine nucleotides degradation
	Urate biosynthesis/inosine 5'-phosphate degradation
	Guanosine nucleotides de novo biosynthesis
	Superpathway of purine nucleotide salvage
	Purine nucleotides de novo biosynthesis
	Guanosine ribonucleotides de novo biosynthesis
KEGG Pathway	Purine metabolism
	Drug metabolism - other enzymes
	Metabolic pathways
PANTHER Pathway	De novo purine biosynthesis
Reactome	Purine ribonucleoside monophosphate biosynthesis
References
Ref 528040	Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. Epub 2006 Feb 17.Low molecular weight indole fragments as IMPDH inhibitors.
Ref 528040	Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. Epub 2006 Feb 17.Low molecular weight indole fragments as IMPDH inhibitors.

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