Drug General Information
Drug ID
D08IRN
Former ID
DNC004310
Drug Name
2,4,5-Triarylimidazole analogue
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551278]
Structure
Download
2D MOL

3D MOL

Formula
C23H20FN5O2
Canonical SMILES
CC(C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)<br />N(C(=O)N)O
InChI
1S/C23H20FN5O2/c1-14(29(31)23(25)30)15-2-4-18(5-3-15)22-27-20(16-6-8-19(24)9-7-16)21(28-22)17-10-12-26-13-11-17/h2-14,31H,1H3,(H2,25,30)(H,27,28)
InChIKey
JVMAHSCWJIZBJE-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) mRNA of human 5-lipoxygenase Target Info Inhibitor [551278]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 5512782,4,5- triarylimidazole inhibitors of IL-1 biosynthesis, Bioorg. Med. Chem. Lett. 5(11):1171-1176 (1995).
Ref 5512782,4,5- triarylimidazole inhibitors of IL-1 biosynthesis, Bioorg. Med. Chem. Lett. 5(11):1171-1176 (1995).

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