Drug Information

Drug General Information
Drug ID
D0EP8X
Former ID
DAP001311
Drug Name
Gamma Hydroxybutyric Acid
Synonyms
Anetamin; GHB; Hydroxyb; Oxybate; SHB; Somsanit; Xyrem; Butyric acid sodium salt; Gamma OH; Oxybate sodium; Utyric acid monosodium salt; EB 27; WY 3478; Gam-OH; Gamma-Hydroxy butyrate; Gamma-Hydroxy sodium butyrate; Gamma-Hydroxybutanoic acid; Gamma-Hydroxybutyrate sodium; Gamma-Hydroxybutyric acid;Gamma-Hydroxybutyric acid decomposition product; Gamma-Hydroxybutyric acid monosodium salt; Gamma-OH; Xyrem (TN); Gamma-Hydroxybutyric acid, sodium salt; Oxy-n-butyric acid; Sodium Oxybate (4-hydroxybutanoic acid); Sodium .gamma.-hydroxybutyrate; Sodium .gamma.-oxybutyrate; AA3E2AF0-AB7A-4A1E-A391-199C049D7162; Butanoic acid, 4-hydroxy-, monosodium salt; Butanoic acid, 4-hydroxy-, sodium salt; Butyric acid, 4-hydroxy-, monosodium salt; Butyric acid, 4-hydroxy-, sodium salt; 3-carboxypropoxy acid; 4 HB; 4-Hydroxy; 4-Hydroxyacid; 4-Hydroxyalkanoic acid; 4-Hydroxybutanoic acid; 4-Hydroxybuttersaeure; 4-Hydroxybutyrate sodium; 4-Hydroxybutyric acid; 4-Hydroxybutyric acid monosodium salt; 4-Hydroxycarboxylic acid; 4-OHB; 4-hydroxy-butyric acid
Drug Type
Small molecular drug
Indication Anesthesia narcolepsy [ICD9: 338, 347; ICD10:G47.4, R20.0] Approved [467952], [536382]
Therapeutic Class
Anesthetics
Company
Jazz Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C4H8O3
InChI
InChI=1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7)
InChIKey
SJZRECIVHVDYJC-UHFFFAOYSA-N
CAS Number
CAS 591-81-1
PubChem Compound ID
10413
PubChem Substance ID
4235, 5088, 794561, 5247515, 7850105, 8145213, 8157522, 10528636, 15146413, 29228914, 29452282, 32853538, 42867017, 47440777, 48185497, 49896246, 57326193, 74490173, 92297559, 103429626, 103933987, 104223670, 104323225, 124954082, 125653427, 126523504, 128286695, 128496528, 129247383, 134224814, 134977465, 135156947, 137005507, 142455246, 160964707, 162833579, 175268868, 178101422, 179293029, 216232054, 223671530, 223922918, 226401522, 241064153, 241101175, 249900959
ChEBI ID
ChEBI:30830
SuperDrug ATC ID
N01AX11; N07XX04
SuperDrug CAS ID
cas=000591811
Target and Pathway
Target(s) GABA(B) receptor Target Info Modulator [556264]
References
Ref 467952(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4711).
Ref 536382Sodium oxybate: a review of its use in the management of narcolepsy. CNS Drugs. 2007;21(4):337-54.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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