Drug General Information
Drug ID
D0W5LS
Former ID
DAP001106
Drug Name
Desoxycorticosterone Pivalate
Synonyms
DOCP; DTMA; Percorten; Cortexone M; Deoxycorticosterone pivalate; Deoxycorticosterone trimethylacetate; Deoxycortolone Pivalate; Deoxycortone pivalate; Deoxycortone trimethylacetate; Desoxycorticosterone trimethylacetate; Desoxycortone pivalate; Percorten M; Percorten Pivalate; Desoxycorticosterone pivalate (USP); Neodin-depositum; Percorten (TN); Corticosterone, deoxy-, pivalate (6CI,7CI); [2-(10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl)-2-oxoethyl] 2,2-dimethylpropanoate; 11-Deoxycorticosterone pivalate; 11-Deoxycorticosterone, pivalate; 11-Deoxycorticosterone, pivalate (8CI); 21-(2,2-Dimethyl-1-oxopropoxy)pregn-4-ene-3,20-dione; 3,20-dioxopregn-4-en-21-yl 2,2-dimethylpropanoate
Drug Type
Small molecular drug
Indication Addison's disease [ICD9: 255.4; ICD10:E27.1-E27.2] Approved [550742]
Therapeutic Class
Antiaddison Agents
Structure
Download
2D MOL

3D MOL

Formula
C26H38O4
Canonical SMILES
CC12CCC3C(C1CCC2C(=O)COC(=O)C(C)(C)C)CCC4=CC(=O)CCC34C
InChI
1S/C26H38O4/c1-24(2,3)23(29)30-15-22(28)21-9-8-19-18-7-6-16-14-17(27)10-12-25(16,4)20(18)11-13-26(19,21)5/h14,18-21H,6-13,15H2,1-5H3/t18-,19-,20-,21+,25-,26-/m0/s1
InChIKey
VVOIQBFMTVCINR-WWMZEODYSA-N
CAS Number
CAS 808-48-0
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:50782
SuperDrug ATC ID
H02AA03
Target and Pathway
Target(s) Mineralocorticoid receptor Target Info Binder [537791]
KEGG Pathway Aldosterone-regulated sodium reabsorption
PathWhiz Pathway Kidney Function
WikiPathways ACE Inhibitor Pathway
References
Ref 550742Drug information of Desoxycorticosterone Pivalate, 2008. eduDrugs.
Ref 537791Characterization of rat brain aldosterone receptors reveals high affinity for corticosterone. Endocrinology. 1983 Dec;113(6):2043-51.

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