Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07SNW
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| Former ID |
DNC006516
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| Drug Name |
1,6-bis(4'-dimethylaminophenyl)-hexa-1,3,5-triene
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [528161] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C22H26N2
|
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| Canonical SMILES |
CN(C)C1=CC=C(C=C1)C=CC=CC=CC2=CC=C(C=C2)N(C)C
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| InChI |
1S/C22H26N2/c1-23(2)21-15-11-19(12-16-21)9-7-5-6-8-10-20-13-17-22(18-14-20)24(3)4/h5-18H,1-4H3/b6-5+,9-7+,10-8+
|
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| InChIKey |
JGQHLETVKDCCET-NRIIQWGUSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [528161] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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