Drug Information
Drug General Information | |||||
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Drug ID |
D01XYJ
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Former ID |
DAP000701
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Drug Name |
Zidovudine
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Synonyms |
AZT; Antiviral; Azidodeoxythymidine; Azidothymidine; Aztec; Retrovir; ZDV; ZVD; Zidovudin; Zidovudina; Zidovudinum; AZT Antiviral; AZT TRANSPLACENTAL CARCINOGENESIS STUDY; Antiviral AZT; Cpd S; Racemic Liposomal AZT; ZIDOVUDINE [AZT]; Zidovudina [Spanish]; Zidovudine EP III; Zidovudinum [Latin]; BW A509U; BWA 509U; BWA509U; K7 [P Ti2 W10 O40]; AZT & EPO; AZT & HPA; AZT & Lymphoblastoid Interferon; AZT & SST; AZT & rsT4; AZT & sCD4; AZT & srCD4; AZT (Antiviral); AZT+PRO 140; AZT, Antiviral; Apo-Zidovudine; BW-A 509U; BW-A509U; BWA-509U; DRG-0004; Intron A & AZT; Novo-Azt; Propolis+AZT; Retrovir (TN); Retrovir(TM); Retrovis (TN); Zidovudine+PRO 140; AZT & Colony-stimulating factor 2; AZT & Concanavalin A (ConA); AZT & GM-CSF; AZT & IFN-alpha; AZT & IL-1; AZT & IL-2; AZT & IL-6; AZT & Li & EPO; AZT & NP (from PHCA or HSA); AZT & PM-19; BW-A-509U; DS-4152 & AZT; Liposomal AZT-SN-1; Liposomal AZT-SN-3; PC-SOD+AZT;RIFN-beta seron & AZT; AZT & CD4(178)-PE 40; AZT & Li & GM-CSF; AZT & Li & IL-1; AZT & Li & IL-6; AZT & rIFN.alpha.2; Racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle); Zidovudine (JAN/USP/INN); Zidovudine [USAN:INN:BAN:JAN]; AZT & rsCD4 & rIFN.alpha.A; SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle); SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle); AZT & Interferon-.alpha.-2; Met-SDF-1.beta. & AZT; Met-SDF-1.beta. & Zidovudine; Interferon AD + 3'-azido-3'-deoxythymidine; 1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine; 3′-Azido-3′-deoxythymidine; 3' Azido 2',3' Dideoxythymidine; 3' Azido 3' deoxythymidine; 3'-Azido-2',3'-Dideoxythymidine; 3'-Azido-3'-deoxythymidine; 3'-Azido-3'-deoxythymidine & Concanavalin A; 3'-Azido-3'-deoxythymidine & Erythropoietin; 3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19; 3'-Azido-3'-deoxythymidine & Interleukin-1; 3'-Azido-3'-deoxythymidine & Interleukin-2; 3'-Azido-3'-deoxythymidine & Interleukin-6; 3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin; 3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1; 3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6; 3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon; 3'-Azido-3'-deoxythymidine & Sho-Saiko-To; 3'-Azido-3'-deoxythymidine (AIDS); 3'-Azido-3'deoxythymidine & Interferon-alpha; 3'-Azidothymidine; 3'-Deoxy-3'-azidothymidine; 3'-azido-3'-deoxythymidine, AZT; 3-Azido-3-deoxythymidine; ZDV
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Drug Type |
Small molecular drug
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Therapeutic Class |
Anti-HIV Agents
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Company |
GlaxoSmithKline
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Structure |
Download2D MOL |
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Formula |
C10H13N5O4
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InChI |
InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
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InChIKey |
HBOMLICNUCNMMY-XLPZGREQSA-N
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CAS Number |
CAS 30516-87-1
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PubChem Compound ID | |||||
PubChem Substance ID |
9419, 595886, 596433, 596437, 596594, 596595, 597291, 597292, 597293, 597457, 597458, 597459, 597460, 597461, 597462, 597463, 597555, 597641, 597664, 597665, 600904, 601536, 602048, 622272, 624122, 643735, 644084, 855980, 7846195, 7847479, 7980906, 8149829, 8173993, 11335699, 11360938, 11364242, 11366804, 11369366, 11372752, 11373842, 11377528, 11461910, 11484570, 11488743, 11491322, 11492147, 11495162, 12013681, 12146009, 14799161
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SuperDrug ATC ID |
J05AF01
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SuperDrug CAS ID |
cas=030516871
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Drug Resistance Mutation (DRM) | |||||
DRM | DRM Info | ||||
Target and Pathway | |||||
Target(s) | HIV reverse transcriptase | Target Info | Inhibitor | [535958] | |
References | |||||
Ref 468057 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4825). | ||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. |
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