Drug General Information
Drug ID	D0Q8BS
Former ID	DIB018109
Drug Name	(S)-alpha-methylhistamine
Synonyms	(S)-alpha-MeHA
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538751]
Structure		Download 2D MOL
Formula	C6H11N3
InChI	InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)/t5-/m0/s1
InChIKey	XNQIOISZPFVUFG-YFKPBYRVSA-N
PubChem Compound ID	6603865
PubChem Substance ID	11111248, 11113573, 26751778, 43223657, 48253918, 48253919, 49846719, 76714568, 103173271, 114636994, 129714815, 131342546, 132621871, 135650426, 139636700, 143178381, 177749645, 229974311, 247986865
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Agonist	[526445]
	Histamine H4 receptor	Target Info	Agonist	[525968]
KEGG Pathway	Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling eventsR-HSA-390650:Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signalingWP1825:GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 538751	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1238).
Ref 525968	Cloning and characterization of a novel human histamine receptor. J Pharmacol Exp Ther. 2001 Mar;296(3):1058-66.
Ref 526445	Characteristics of recombinantly expressed rat and human histamine H3 receptors. Eur J Pharmacol. 2002 Oct 18;453(1):33-41.

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