Drug Information
Drug General Information | |||||
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Drug ID |
D0K0TC
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Former ID |
DAP000051
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Drug Name |
Sertraline
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Synonyms |
Lustral; SRE; Sertralina; Sertralinum; Sertralina [Spanish]; Sertraline [Zoloft]; Sertralinum [Latin]; CP 51974; Cp 51974; Apo-Sertraline; Lustral (TN); Sertraline (INN); Sertraline (Zoloft); Sertraline [INN:BAN]; Zoloft (TN); (+)-Sertraline; (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine; (1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine; (1S-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antidepressants
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Company |
Pfizer Inc
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Structure |
Download2D MOL |
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Formula |
C17H17Cl2N
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InChI |
InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1
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InChIKey |
VGKDLMBJGBXTGI-SJCJKPOMSA-N
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CAS Number |
CAS 79617-96-2
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PubChem Compound ID | |||||
PubChem Substance ID |
9455, 7849419, 7980593, 8192230, 11372017, 11374862, 11484121, 11488309, 11490894, 11493046, 14776364, 14923174, 17425146, 24723455, 26753299, 29215139, 43125164, 46505341, 47870036, 48019284, 48243732, 48394276, 48416536, 49665783, 49699249, 49995188, 50105682, 50105683, 50105684, 50105685, 50723729, 53788480, 57288837, 57316967, 57654971, 85148370, 85789675, 90341218, 92714411, 93166926, 93167211, 99445038, 103213015, 103937473, 104342622, 117463757, 117475932, 118047120, 121264488, 121363704
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ChEBI ID |
ChEBI:9123
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SuperDrug ATC ID |
N06AB06
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SuperDrug CAS ID |
cas=079617962
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Target and Pathway | |||||
Target(s) | Sodium-dependent serotonin transporter | Target Info | Inhibitor | [536303], [536503] | |
KEGG Pathway | Serotonergic synapse | ||||
NetPath Pathway | TCR Signaling Pathway | ||||
References | |||||
Ref 468027 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4798). | ||||
Ref 536306 | Emerging treatments for depression. Expert Opin Pharmacother. 2006 Dec;7(17):2323-39. |
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