Drug Information
Drug General Information | |||||
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Drug ID |
D0R7JT
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Former ID |
DAP001105
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Drug Name |
Fludrocortisone
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Synonyms |
Alflorone; Astonin; FCOL; Florinef; Fludrocortisona; Fludrocortisonum; Fludrocortone; Fludrone; Fludronef; Fluodrocortisone; Fluohydrisone; Fluohydrocortisone; Fluorocortisol; Fluorocortisone; Astonin H; Astonin Merck; Merck Brand of Fludrocortisone; StC 1400; U 5963; ZK5; Astonin-H; F-COL; F-Cortef;Florinef (TN); Fludrocortisona [INN-Spanish]; Fludrocortisone (INN); Fludrocortisone [INN:BAN]; Fludrocortisonum [INN-Latin]; Merck, Astonin; Astonin-H (TN); Hydrocortisone-9alpha-fluoro; Pregn-4-ene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-(8CI); (11beta)-9-Fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione; (8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one; 9 .alpha. FF; 9 Fluoro 17 Hydroxycortisone; 9 Fluorocortisol; 9 Fluorohydrocortisone; 9 alpha FF; 9 alpha Fludrohydrocortisone; 9 alpha Fluoro 17 Hydroxycorticosterone; 9 alpha Fluorohydrocortisone; 9 alpha-Fludrocortisone; 9 alpha-Fluoro-17-Hydroxycorticosterone; 9 alpha-Fluorocortisol; 9 alpha-Fluorohydrocortisone; 9-Fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione; 9-Fluoro-11.beta.,17,21-trihydroxypregn-4-ene-3,20-dione; 9-Fluoro-11beta,17,21-trihydroxypregn-4-ene-3,20-dione; 9-Fluoro-17-Hydroxycortisone; 9-Fluorocortisol; 9-Fluorohydrocortisone; 9-alpha-Fludrocortisone; 9-alpha-Fluoro-17-hydroxycorticosterone; 9-alpha-Fluorocortisol; 9-alpha-Fluorohydrocortisone; 9.alpha.-Fluoro-11.beta.,17.alpha.,21-trihydroxy-4-pregnene-3,20-dione; 9.alpha.-Fluoro-17-hydroxycorticosterone; 9.alpha.-Fluorocortisol; 9.alpha.-Fluorohydrocortisone; 9alpha-Fludrocortisone; 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione; 9alpha-Fluoro-17-hydroxycorticosterone; 9alpha-Fluoro-hydrocortisone; 9alpha-Fluorocortisol
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antiinflammatory Agents
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Structure |
Download2D MOL |
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Formula |
C21H29FO5
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InChI |
InChI=1S/C21H29FO5/c1-18-7-5-13(24)9-12(18)3-4-15-14-6-8-20(27,17(26)11-23)19(14,2)10-16(25)21(15,18)22/h9,14-16,23,25,27H,3-8,10-11H2,1-2H3/t14-,15-,16-,18-,19-,20-,21-/m0/s1
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InChIKey |
AAXVEMMRQDVLJB-BULBTXNYSA-N
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CAS Number |
CAS 127-31-1
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PubChem Compound ID | |||||
PubChem Substance ID |
9217, 76336, 7891224, 7979235, 8172141, 10321611, 15375738, 24702328, 34673521, 46508616, 46508716, 48416020, 50019673, 50125791, 50864760, 56352851, 57311202, 71831474, 85286070, 96024662, 104234355, 104310733, 117567350, 123059725, 126651363, 126687973, 127307282, 127379594, 134338350, 135269929, 135650268, 137003338, 139326855, 144080988, 144206253, 144206895, 160963328, 160964032, 162176728, 164841599, 170464959, 175266519, 179214416, 196108113, 196404089, 223657072, 226396521, 249910373
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ChEBI ID |
ChEBI:50885
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SuperDrug ATC ID |
H02AA02
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SuperDrug CAS ID |
cas=000127311
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Target and Pathway | |||||
Target(s) | Mineralocorticoid receptor | Target Info | Agonist | [535856], [537575] | |
KEGG Pathway | Aldosterone-regulated sodium reabsorption | ||||
PathWhiz Pathway | Kidney Function | ||||
WikiPathways | ACE Inhibitor Pathway | ||||
References | |||||
Ref 538426 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 010060. | ||||
Ref 539899 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2873). |
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