Drug General Information
Drug ID	D0X0IH
Former ID	DNC010490
Drug Name	BENZYLIMIDAZOLE
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530679]
Structure		Download 2D MOL 3D MOL
Formula	C10H10N2
Canonical SMILES	C1=CC=C(C=C1)CN2C=CN=C2
InChI	1S/C10H10N2/c1-2-4-10(5-3-1)8-12-7-6-11-9-12/h1-7,9H,8H2
InChIKey	KKKDZZRICRFGSD-UHFFFAOYSA-N
PubChem Compound ID	77918
Target and Pathway
Target(s)	Cytochrome P450 11B1, mitochondrial	Target Info	Inhibitor	[530679]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Glucocorticoid biosynthesis
	Mineralocorticoid biosynthesis
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
PathWhiz Pathway	Steroidogenesis
Reactome	Glucocorticoid biosynthesis
	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Oxidation by Cytochrome P450
	Metabolism of steroid hormones and vitamin D
	Corticotropin-releasing hormone
References
Ref 530679	J Med Chem. 2010 Feb 25;53(4):1712-25.Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2).
Ref 530679	J Med Chem. 2010 Feb 25;53(4):1712-25.Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2).

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