Drug General Information
Drug ID	D0G8AG
Former ID	DNC006029
Drug Name	BN-82685
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527791]
Structure		Download 2D MOL 3D MOL
Formula	C12H15N3O2S
Canonical SMILES	CC1=NC2=C(S1)C(=O)C=C(C2=O)NCCN(C)C
InChI	1S/C12H15N3O2S/c1-7-14-10-11(17)8(13-4-5-15(2)3)6-9(16)12(10)18-7/h6,13H,4-5H2,1-3H3
InChIKey	MTUYOFGUEXWKLC-UHFFFAOYSA-N
PubChem Compound ID	10286059
Target and Pathway
Target(s)	M-phase inducer phosphatase 3	Target Info	Inhibitor	[527791]
KEGG Pathway	Cell cycle
	Oocyte meiosis
	Progesterone-mediated oocyte maturation
	MicroRNAs in cancer
PANTHER Pathway	p53 pathway
Pathway Interaction Database	ATR signaling pathway
	ATM pathway
	PLK1 signaling events
	PLK3 signaling events
Reactome	Polo-like kinase mediated events
	Cyclin B2 mediated events
	Activation of ATR in response to replication stress
	RHO GTPases activate PKNs
	Cyclin A/B1 associated events during G2/M transition
	Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
WikiPathways	Monoamine Transport
	DNA Damage Response
	ATM Signaling Pathway
	Integrated Pancreatic Cancer Pathway
	Mitotic G2-G2/M phases
	Cell Cycle
	Cell Cycle Checkpoints
	miRNA Regulation of DNA Damage Response
References
Ref 527791	Bioorg Med Chem Lett. 2006 Jan 1;16(1):171-5. Epub 2005 Oct 10.Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C.
Ref 527791	Bioorg Med Chem Lett. 2006 Jan 1;16(1):171-5. Epub 2005 Oct 10.Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C.

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