Drug Information

Drug General Information
Drug ID
D0D2MS
Former ID
DNC008408
Drug Name
5-methylenearisteromycin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529335]
Structure
Download
2D MOL

3D MOL
Formula
C12H15N5O3
Canonical SMILES
C=C1C(C(C(C1N2C=NC3=C2N=CN=C3N)O)O)CO
InChI
1S/C12H15N5O3/c1-5-6(2-18)9(19)10(20)8(5)17-4-16-7-11(13)14-3-15-12(7)17/h3-4,6,8-10,18-20H,1-2H2,(H2,13,14,15)/t6-,8+,9+,10-/m0/s1
InChIKey
REGXGANNNMTWAW-ZQNVIIHSSA-N
PubChem Compound ID
11737492
Target and Pathway
Target(s) Adenosylhomocysteinase Target Info Inhibitor [529335]
BioCyc Pathway Superpathway of methionine degradation
Methionine degradation
Cysteine biosynthesis
KEGG Pathway Cysteine and methionine metabolism
Metabolic pathways
PathWhiz Pathway Selenoamino Acid Metabolism
Betaine Metabolism
Methionine Metabolism
WikiPathways Metabolism of amino acids and derivatives
Trans-sulfuration and one carbon metabolism
One Carbon Metabolism
Trans-sulfuration pathway
Phase II conjugation
Folate Metabolism
References
Ref 529335Bioorg Med Chem. 2008 Apr 1;16(7):3809-15. Epub 2008 Jan 30.Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.
Ref 529335Bioorg Med Chem. 2008 Apr 1;16(7):3809-15. Epub 2008 Jan 30.Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.