Drug Information

Drug General Information
Drug ID
D07IRF
Former ID
DAP001548
Drug Name
Prasugrel
Synonyms
Effient (TN)
Drug Type
Small molecular drug
Indication Acute coronary syndrome [ICD9: 444; ICD10:I74] Approved [530677], [542562]
Company
Lilly; Daiichi Sankyo
Structure
Download
2D MOL

3D MOL
Formula
C20H20FNO3S
InChI
InChI=1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3
InChIKey
DTGLZDAWLRGWQN-UHFFFAOYSA-N
CAS Number
CAS 150322-43-3
PubChem Compound ID
6918456
PubChem Substance ID
12015290, 14755496, 17194902, 43529826, 50546070, 57371939, 92718874, 92729702, 93581167, 99007939, 99246149, 99437235, 99443238, 114788002, 118844214, 124757123, 124772077, 124899264, 125003151, 125163927, 125341579, 126621261, 126647919, 126667058, 127783798, 131299795, 134357981, 135262112, 136023837, 136948147, 137234076, 140025693, 143497952, 144155824, 151980606, 152237337, 152258668, 152344171, 160647505, 160682499, 160967853, 162189604, 163772054, 164823943, 164830144, 165237612, 166232249, 170501032, 172085106, 172089108
Target and Pathway
Target(s) P2Y purinoceptor 12 Target Info Inhibitor [530677]
KEGG Pathway Platelet activation
Reactome P2Y receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Signal amplification
GPCR ligand binding
GPCR downstream signaling
References
Ref 530677Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
Ref 542562(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7562).
Ref 530677Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.

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