Drug Information

Drug General Information
Drug ID
D08KZJ
Former ID
DIB019070
Drug Name
CAY 10471
Synonyms
CAY10471; CAY-10471
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539206]
Structure
Download
2D MOL
Formula
C21H21FN2O4S
InChI
InChI=1S/C21H21FN2O4S/c1-23(29(27,28)16-9-6-14(22)7-10-16)15-8-11-20-18(12-15)17-4-2-3-5-19(17)24(20)13-21(25)26/h2-7,9-10,15H,8,11-13H2,1H3,(H,25,26)
InChIKey
CANCTKXGRVNXFP-UHFFFAOYSA-N
PubChem Compound ID
11384493
PubChem Substance ID
16478517, 23537293, 42463687, 79672785, 124963955, 125335122, 135650058, 174006831, 196377484, 223704990, 241124678, 242586145, 248209474, 252457748
Target and Pathway
Target(s) Putative G-protein coupled receptor 44 Target Info Agonist [527436]
Reactome Prostanoid ligand receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 539206(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1905).
Ref 527436Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist. J Med Chem. 2005 Feb 24;48(4):897-900.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.