Drug Information

Drug General Information
Drug ID
D0HD2G
Former ID
DIB020709
Drug Name
phloretin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467623]
Structure
Download
2D MOL
Formula
C15H14O5
InChI
InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2
InChIKey
VGEREEWJJVICBM-UHFFFAOYSA-N
PubChem Compound ID
4788
PubChem Substance ID
4036, 477076, 841166, 885022, 3152290, 6900044, 7979953, 8141738, 8144209, 8152940, 11111666, 11111667, 11341604, 11361787, 11364189, 11366751, 11369313, 11372170, 11374941, 11377475, 11484537, 11487189, 11488497, 11490851, 11492986, 11495109, 11537656, 14750659, 17405570, 22425581, 24278652, 24771297, 24887442, 26613299, 26679936, 26725279, 26747651, 26753632, 26759355, 29204475, 29223872, 46500461, 47440053, 47736274, 47736275, 47885227, 47959549, 48334288, 48421899, 49760075
Target and Pathway
Target(s) AQP9 Target Info Inhibitor [543918]
ClC-3 Target Info Blocker (channel blocker) [543925]
Sodium-dependent vitamin C transporter 1 Target Info Inhibitor [525494]
References
Ref 467623(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4285).
Ref 525494A family of mammalian Na+-dependent L-ascorbic acid transporters. Nature. 1999 May 6;399(6731):70-5.
Ref 543918(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 696).
Ref 543925(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 702).

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