Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01BIZ
|
||||
| Former ID |
DNC004025
|
||||
| Drug Name |
Z-Arg-Leu-Val-Agly-Trp-Val-Ala-NH2
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [526417] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C45H67N13O9
|
||||
| Canonical SMILES |
CC(C)CC(C(=O)NC(C(C)C)C(=O)NNC(=O)NC(CC1=CNC2=CC=CC=C21<br />)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=<br />O)OCC3=CC=CC=C3
|
||||
| InChI |
1S/C45H67N13O9/c1-24(2)20-33(52-38(60)32(18-13-19-49-43(47)48)54-45(66)67-23-28-14-9-8-10-15-28)39(61)56-36(26(5)6)42(64)57-58-44(65)53-34(21-29-22-50-31-17-12-11-16-30(29)31)40(62)55-35(25(3)4)41(63)51-27(7)37(46)59/h8-12,14-17,22,24-27,32-36,50H,13,18-21,23H2,1-7H3,(H2,46,59)(H,51,63)(H,52,60)(H,54,66)(H,55,62)(H,56,61)(H,57,64)(H4,47,48,49)(H2,53,58,65)
|
||||
| InChIKey |
TXGCKASBHJKJOM-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cathepsin B | Target Info | Inhibitor | [526417] | |
| Cathepsin K | Target Info | Inhibitor | [526417] | ||
| Reactome | Collagen degradation | ||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.