TTD | Drug: D02IVR

Drug General Information
Drug ID	D02IVR
Former ID	DIB020620
Drug Name	ONO-DI-004
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539215]
Structure		Download 2D MOL
Formula	C24H38O6
InChI	InChI=1S/C24H38O6/c1-3-4-5-15(2)12-18(25)10-11-19-20(23(28)14-22(19)27)13-21(26)16-6-8-17(9-7-16)24(29)30/h10-11,15-20,22,25,27H,3-9,12-14H2,1-2H3,(H,29,30)/b11-10+/t15-,16?,17?,18+,19+,20+,22+/m0/s1
InChIKey	KWRRIFVHVJWXPU-HVCOQRSISA-N
PubChem Compound ID	5311227
PubChem Substance ID	7979733, 11056358, 14807098, 39340935, 52805565, 85742106, 114155604, 135650772, 227500079
Target and Pathway
Target(s)	Prostaglandin E2 receptor, EP1 subtype	Target Info	Agonist	[525735]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Pathways in cancer
PANTHER Pathway	PI3 kinase pathway
Reactome	Prostanoid ligand receptors
Reactome	G alpha (q) signalling events
WikiPathways	Prostaglandin Synthesis and Regulation
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539215	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1914).
Ref 525735	The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs. Endocrinology. 2000 Apr;141(4):1554-9.

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Drug Information