Drug General Information
Drug ID
D00AQR
Former ID
DIB019585
Drug Name
compound 72 [WO2013026806]
Synonyms
EHT 5372; compound 8c [PMID 25264830]
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532979]
Structure
Download
2D MOL
Formula
C17H12ClN5OS
InChI
InChI=1S/C17H12ClN5OS/c1-24-15(19)17-23-12-7-6-11-13(14(12)25-17)16(21-8-20-11)22-10-4-2-9(18)3-5-10/h2-8,19H,1H3,(H,20,21,22)
InChIKey
BGXZIBSLBRKDTP-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B Target Info Inhibitor [543537]
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A Target Info Inhibitor [543536]
References
Ref 532979Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part II. Molecules. 2014 Sep 26;19(10):15411-39.
Ref 543536(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2009).
Ref 543537(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2010).

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