Drug Information
Drug General Information | |||||
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Drug ID |
D0O2SR
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Former ID |
DAP001409
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Drug Name |
Nicorandil
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Synonyms |
Adancor; Dancor; Ikorel; Nicorandilum; Sigmart; Aventis Brand of Nicorandil; Aventis Pharma Brand of Nicorandil; Merck Brand of Nicorandil; Merck Lipha Sante Brand of Nicorandil; Nicorandil Aventis Brand; Nicorandil Merck Brand; Rhone Poulenc Rorer Brand of Nicorandil; SG 75; SG75; Ikorel (TN); Nicorandilum [INN-Latin]; RP-46417; Rhone-Poulenc Rorer Brand of Nicorandil; SG-75; Sigmart (TN); Nitrate, 2-Nicotinamidethyl; Nitrate, 2-Nicotinamidoethyl; N-(2-Hydroxyethyl)nicotinamide nitrate; Nicorandil (JP15/USAN/INN); Nicorandil [USAN:BAN:INN:JAN]; N-(2-Hydroxyethyl)nicotinamide nitrate (ester); N-[2-(Nitrooxy)ethyl]pyridine-3-carboxamide; 2 Nicotinamidethyl Nitrate; 2 Nicotinamidoethyl Nitrate; 2-(Nicotinamido)ethyl nitrat; 2-(Pyridine-3-carboxamido)ethyl Nitrate; 2-(pyridine-3-carbonylamino)ethyl nitrate; 2-Nicotinamidethyl Nitrate; 2-Nicotinamidoethyl nitrate; 2-[(pyridin-3-ylcarbonyl)amino]ethylnitrat
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Drug Type |
Small molecular drug
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Therapeutic Class |
Vasodilator Agents
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Company |
Chugai; Roche; Sanofi-Aventis; Merk KGaA; Pfizer; 3M Pharmaceutical
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Structure |
Download2D MOL |
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Formula |
C8H9N3O4
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InChI |
InChI=1S/C8H9N3O4/c12-8(7-2-1-3-9-6-7)10-4-5-15-11(13)14/h1-3,6H,4-5H2,(H,10,12)
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InChIKey |
LBHIOVVIQHSOQN-UHFFFAOYSA-N
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CAS Number |
CAS 65141-46-0
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PubChem Compound ID | |||||
PubChem Substance ID |
586024, 1916767, 5278428, 7848872, 7980121, 8180260, 11114278, 12014252, 14797708, 26719873, 34712504, 46386683, 49681787, 49834470, 50031637, 50104982, 53788263, 57313114, 77340175, 81040873, 81093242, 85148372, 85788091, 87561371, 88477210, 92308506, 92308908, 92721812, 103198688, 103858488, 104253442, 104353163, 106136910, 115354362, 117540196, 121362729, 124659032, 124757566, 124799992, 125164370, 125355483, 125433860, 126603603, 126627520, 126657351, 126667237, 128464451, 131322571, 134338617, 135008321
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SuperDrug ATC ID |
C01DX16
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SuperDrug CAS ID |
cas=065141460
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Target and Pathway | |||||
Target(s) | SUR2-type K(ATP) channel | Target Info | Activator | [535088], [535269], [536105] | |
References | |||||
Ref 536497 | Pharmacologic therapeutics for cardiac reperfusion injury. Expert Opin Emerg Drugs. 2007 Sep;12(3):367-88. | ||||
Ref 539541 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2411). | ||||
Ref 535088 | The molecular basis of the specificity of action of K(ATP) channel openers. EMBO J. 2000 Dec 15;19(24):6644-51. | ||||
Ref 535269 | Structural basis for the interference between nicorandil and sulfonylurea action. Diabetes. 2001 Oct;50(10):2253-9. | ||||
Ref 536105 | A functional role of the C-terminal 42 amino acids of SUR2A and SUR2B in the physiology and pharmacology of cardiovascular ATP-sensitive K(+) channels. J Mol Cell Cardiol. 2005 Jul;39(1):1-6. Epub 2005 Feb 5. |
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